High Rates of Genome Rearrangements and Pathogenicity of Shigella spp

• Published in: Frontiers in microbiology Vol. 12; p. 628622
• Main Authors: Seferbekova, Zaira, Zabelkin, Alexey, Yakovleva, Yulia, Afasizhev, Robert, Dranenko, Natalia O, Alexeev, Nikita, Gelfand, Mikhail S, Bochkareva, Olga O
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 12.04.2021
• Subjects: E3 ubiquitin-ligases; Escherichia coli; Microbiology; pathogens; recombination; Shigella; recombination; pathogens; E3 ubiquitin-ligases; Escherichia coli; rearrangements; IS; Shigella

are pathogens originating within the lineage but frequently classified as a separate genus. genomes contain numerous insertion sequences (ISs) that lead to pseudogenisation of affected genes and an increase of non-homologous recombination. Here, we study 414 genomes of and strains to assess the cont...