Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even though COVID-19 vaccinations are available now, there is still an urgent need to find potential treatments to ease the effects of...

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Bibliographic Details
Published inPneumonia Vol. 13; no. 1; p. 14
Main Authors Aslan, Anolin, Aslan, Cynthia, Zolbanin, Naime Majidi, Jafari, Reza
Format Journal Article
LanguageEnglish
Published England BioMed Central 06.12.2021
BMC
Subjects
Acute respiratory distress syndrome
ARDS
COVID-19
Pandemics
Review
SARS-CoV-2
Acute respiratory distress syndrome
COVID-19
SARS-CoV-2
Pandemics
ARDS
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Summary:COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even though COVID-19 vaccinations are available now, there is still an urgent need to find potential treatments to ease the effects of COVID-19 on already sick patients. Multiple experimental drugs have been approved by the FDA with unknown efficacy and possible adverse effects. Probably the increasing number of studies worldwide examining the potential COVID-19 related therapies will help to identification of effective ARDS treatment. In this review article, we first provide a summary on immunopathology of ARDS next we will give an overview of management of patients with COVID-19 requiring intensive care unit (ICU), while focusing on the current treatment strategies being evaluated in the clinical trials in COVID-19-induced ARDS patients.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:2200-6133
2200-6133
DOI:10.1186/s41479-021-00092-9