Effects of vaccination, new SARS-CoV-2 variants and reinfections on post-COVID-19 complications

Post-COVID-19 complications involve a variety of long-lasting health complications emerging in various body systems. Since the prevalence of post-COVID-19 complications ranges from 8-47% in COVID-19 survivors, it represents a formidable challenge to COVID-19 survivors and the health care system. Pos...

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Published inFrontiers in public health Vol. 10; p. 903568
Main Authors Orendáčová, Mária, Kvašňák, Eugen
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 29.07.2022
Subjects
COVID-19
Humans
mechanisms
new research directions
post-COVID-19 complications
prevention strategies
Public Health
Reinfection
SARS-CoV-2
SARS-CoV-2 new variants
Vaccination
vaccination status
Viral Vaccines
post-COVID-19 complications
prevention strategies
vaccination status
SARS-CoV-2 reinfections
new research directions
mechanisms
SARS-CoV-2 new variants
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Summary:Post-COVID-19 complications involve a variety of long-lasting health complications emerging in various body systems. Since the prevalence of post-COVID-19 complications ranges from 8-47% in COVID-19 survivors, it represents a formidable challenge to COVID-19 survivors and the health care system. Post-COVID-19 complications have already been studied in the connection to risk factors linked to their higher probability of occurrence and higher severity, potential mechanisms underlying the pathogenesis of post-COVID-19 complications, and their functional and structural correlates. Vaccination status has been recently revealed to represent efficient prevention from long-term and severe post-COVID-19 complications. However, the exact mechanisms responsible for vaccine-induced protection against severe and long-lasting post-COVID-19 complications remain elusive. Also, to the best of our knowledge, the effects of new SARS-CoV-2 variants and SARS-CoV-2 reinfections on post-COVID-19 complications and their underlying pathogenesis remain to be investigated. This hypothesis article will be dedicated to the potential effects of vaccination status, SARS-CoV-2 reinfections, and new SARS-CoV-2 variants on post-COVID-19 complications and their underlying mechanisms Also, potential prevention strategies against post-COVID complications will be discussed.
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Reviewed by: Rafael B. Polidoro, Indiana University Bloomington, United States; Pragya Dhruv Yadav, ICMR-National Institute of Virology, India
This article was submitted to Infectious Diseases - Surveillance, Prevention and Treatment, a section of the journal Frontiers in Public Health
Edited by: Chiara de Waure, University of Perugia, Italy
ISSN:2296-2565
2296-2565
DOI:10.3389/fpubh.2022.903568