Desmocollin 1 and desmoglein 1 expression in human epidermis and keratinizing oral mucosa : a comparative immunohistochemical and molecular study

• Published in: Archives of Dermatological Research Vol. 297; no. 1; pp. 31 - 38
• Main Authors: DONETTI, Elena, BEDONI, Marzia, BOSCHINI, Elena, DELLAVIA, Claudia, BARAJON, Isabella, GAGLIANO, Nicoletta
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.07.2005; Springer Nature B.V
• Subjects: Adult; Biological and medical sciences; Dermatology; Desmocollins; Desmoglein 1 - analysis; Epidermis - chemistry; Female; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Keratinocytes - chemistry; Male; Medical sciences; Membrane Glycoproteins - analysis; Microscopy, Immunoelectron; Mouth Mucosa - chemistry; Reverse Transcriptase Polymerase Chain Reaction; Human; Immunohistochemistry; RNA-directed DNA polymerase; Enzyme; Dermatology; Transferases; keratinocytes, electron microscopy; Epidermis; Desmosome; Cadherin; Electron microscopy; Oral cavity; Anatomic pathology; Nucleotidyltransferases; RT-PCR; Desmoglein 1; Keratinocyte; desmosomal cadherins; Molecular biology; Reverse transcription polymerase chain reaction; Comparative study

Epidermis and keratinizing oral mucosa (KOM) are effective barriers against a wide spectrum of insults. The optimal form of protection provided by each epithelium is determined also by the molecular composition of desmosomes. Up to now, the expression of the "skin type" desmosomal cadherin...