COVID-19 and Hypertension: The What, the Why, and the How

It has been a year since the coronavirus disease 2019 (COVID-19) was declared pandemic and wreak havoc worldwide. Despite meticulous research has been done in this period, there are still much to be learn from this novel coronavirus. Globally, observational studies have seen that majority of the pat...

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Published inFrontiers in physiology Vol. 12; p. 665064
Main Authors Muhamad, Shah-Abas, Ugusman, Azizah, Kumar, Jaya, Skiba, Dominik, Hamid, Adila A, Aminuddin, Amilia
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 03.05.2021
Subjects
coronavirus
COVID-19
endothelial dysfunction
hypertension
Physiology
renin angiotensin system
SARS-CoV-2
COVID-19
SARS-CoV-2
coronavirus
renin angiotensin system
angiotensin converting enzyme 2
endothelial dysfunction
hypertension
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Summary:It has been a year since the coronavirus disease 2019 (COVID-19) was declared pandemic and wreak havoc worldwide. Despite meticulous research has been done in this period, there are still much to be learn from this novel coronavirus. Globally, observational studies have seen that majority of the patients with COVID-19 have preexisting hypertension. This raises the question about the possible relationship between COVID-19 and hypertension. This review summarizes the current understanding of the link between hypertension and COVID-19 and its underlying mechanisms.
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Edited by: Claudia Penna, University of Turin, Italy
These authors have contributed equally to this work
This article was submitted to Vascular Physiology, a section of the journal Frontiers in Physiology
Reviewed by: Siu-Lung Chan, Harvard Medical School, United States; Ana Cristina Simões E. Silva, Federal University of Minas Gerais, Brazil
ISSN:1664-042X
1664-042X
DOI:10.3389/fphys.2021.665064