Recent advances in electrospun nanofibers for wound healing

Electrospun nanofibers represent a novel class of materials that show great potential in many biomedical applications including biosensing, regenerative medicine, tissue engineering, drug delivery and wound healing. In this work, we review recent advances in electrospun nanofibers for wound healing....

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Bibliographic Details
Published inNanomedicine Vol. 12; no. 11; pp. 1335 - 1352
Main Authors Chen, Shixuan, Liu, Bing, Carlson, Mark A, Gombart, Adrian F, Reilly, Debra A, Xie, Jingwei
Format Journal Article Book Review
LanguageEnglish
Published England Future Medicine Ltd 01.06.2017
Subjects
3-D printers
Animals
Antimicrobial agents
Bandages
Burns
Collagen
Cytokines
Dietary fiber
Drug Delivery Systems - methods
Electrochemical Techniques - instrumentation
Electrochemical Techniques - methods
electrospun nanofibers
Equipment Design
Foot diseases
Growth factors
Humans
local drug delivery
Nanofibers - chemistry
Nanofibers - therapeutic use
Nanotechnology - instrumentation
Nanotechnology - methods
Pressure ulcers
Proteins
Regeneration - drug effects
Regenerative Medicine - instrumentation
Regenerative Medicine - methods
Review
scaffold
Skin
Skin - drug effects
Skin Physiological Phenomena - drug effects
skin regeneration
Skin, Artificial
Sutures
Tissue Scaffolds - chemistry
Wound healing
Wound Healing - drug effects
United States > US
wound healing
electrospun nanofibers
scaffold
local drug delivery
skin regeneration
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Summary:Electrospun nanofibers represent a novel class of materials that show great potential in many biomedical applications including biosensing, regenerative medicine, tissue engineering, drug delivery and wound healing. In this work, we review recent advances in electrospun nanofibers for wound healing. This article begins with a brief introduction on the wound, and then discusses the unique features of electrospun nanofibers critical for wound healing. It further highlights recent studies that have used electrospun nanofibers for wound healing applications and devices, including sutures, multifunctional dressings, dermal substitutes, engineered epidermis and full-thickness skin regeneration. Finally, we finish with conclusions and future perspective in this field.
ISSN:1743-5889
1748-6963
DOI:10.2217/nnm-2017-0017