Predictors of Comorbid Conditions in Women Who Carry an FMR1 Premutation

• Published in: Frontiers in psychiatry Vol. 12; p. 715922
• Main Authors: Allen, Emily Graves, Charen, Krista, Hipp, Heather S, Shubeck, Lisa, Amin, Ashima, He, Weiya, Hunter, Jessica Ezzell, Shelly, Katharine E, Sherman, Stephanie L
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 01.10.2021
• Subjects: FMR1; fragile X syndrome; FXPOI; FXTAS; premutation; Psychiatry; FXPOI; FMR1; premutation; FXTAS; fragile X syndrome

Women who carry an premutation (PM) can experience two well-established PM-associated disorders: fragile X-associated primary ovarian insufficiency (FXPOI, affects ~20-30% carriers) and fragile X-associated tremor-ataxia syndrome (FXTAS, affects ~6-15% carriers); however, emerging evidence indicates...