Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses
Purpose To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo‐planar diffusion‐weighted (EPDW) MR images are useful in the differential diagnosis of retroperitoneal masses. Materials and Methods In 50 patients with known retroperitoneal masses, EPDW images...
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Published in | Journal of magnetic resonance imaging Vol. 20; no. 4; pp. 735 - 742 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Hoboken
Wiley Subscription Services, Inc., A Wiley Company
01.10.2004
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Subjects | |
Online Access | Get full text |
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Summary: | Purpose
To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo‐planar diffusion‐weighted (EPDW) MR images are useful in the differential diagnosis of retroperitoneal masses.
Materials and Methods
In 50 patients with known retroperitoneal masses, EPDW images were performed with b‐factors of 0–1100 seconds/mm2. The final histologic diagnoses of these lesions were as follows: 12 malignant lymphomas, four other malignant mesenchymal neoplasms, 25 malignant epithelial neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions. The ADC values obtained for the solid portion of the lesions were used to represent each lesion, and the values of the histologic groups were compared.
Results
The respective value of ADC for 12 malignant lymphomas, four other mesenchymal neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions were as follows: 0.66 ± 0.26, 1.26 ± 0.50, 0.90 ± 0.20, 1.87 ± 0.48, 1.32 ± 0.20 × 10−3 mm2/second. The ADC value of the malignant lymphoma was significantly lower than that of the other malignant mesenchymal lesions, and was also lower than the ADC of the benign lesions. The ADC value of the malignant epithelial neoplasms was lower than that of the benign mesenchymal tumors. The ADC values of the malignant and benign lesions were 0.94 ± 0.30 and 1.75 ± 0.49 × 10−3 mm2/second, respectively, which also demonstrated a significant difference.
Conclusion
ADC values calculated from EPDW MR images may provide useful information in the differential diagnosis of retroperitoneal masses. J. Magn. Reson. Imaging 2004;20:735–742. © 2004 Wiley‐Liss, Inc. |
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Bibliography: | ArticleID:JMRI20149 istex:8282A0E6E86F0B1ED74FE87198BA9851944739D8 ark:/67375/WNG-C4W5W49Z-L ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1053-1807 1522-2586 |
DOI: | 10.1002/jmri.20149 |