Tumor-Associated Macrophages as Targets for Cancer Therapy

An editorial argues that tumor-associated macrophages (TAMs) can either directly or indirectly contribute to tumor survival, growth, and metastasis and these cells could be a potential target for antitumor therapy.

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Bibliographic Details
Published inJNCI : Journal of the National Cancer Institute Vol. 90; no. 21; pp. 1583 - 1584
Main Authors Wahl, Larry M., Kleinman, Hynda K.
Format Journal Article
LanguageEnglish
Published United States Oxford University Press 04.11.1998
Oxford Publishing Limited (England)
Subjects
Animals
Antineoplastic Agents - pharmacology
Cancer
Drug therapy
Editorials
Humans
Hydroxyquinolines - pharmacology
Interferon-gamma - metabolism
Interleukin-12 - metabolism
Interleukin-18 - metabolism
Macrophages - drug effects
Macrophages - metabolism
Neoplasms, Experimental - drug therapy
Neoplasms, Experimental - immunology
Neoplasms, Experimental - metabolism
Plasminogen Activator Inhibitor 2 - biosynthesis
Plasminogen Activator Inhibitor 2 - metabolism
Tumors
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Summary:An editorial argues that tumor-associated macrophages (TAMs) can either directly or indirectly contribute to tumor survival, growth, and metastasis and these cells could be a potential target for antitumor therapy.
Bibliography:ark:/67375/HXZ-2H8MPDL2-W
istex:8E02435FC5610895F59BEDC709958F6C11A95044
SourceType-Other Sources-1
content type line 63
ObjectType-Editorial-2
ObjectType-Commentary-1
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/90.21.1583