Non-enzymatic sensors based on in situ laser-induced synthesis of copper-gold and gold nano-sized microstructures

• Published in: Talanta (Oxford) Vol. 167; pp. 201 - 207
• Main Authors: Panov, Maxim S., Vereshchagina, Olga A., Ermakov, Sergey S., Tumkin, Ilya I., Khairullina, Evgeniia M., Skripkin, Mikhail Yu, Mereshchenko, Andrey S., Ryazantsev, Mikhail N., Kochemirovsky, Vladimir A.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.05.2017
• Subjects: biosensors; Copper; crystallization; Cyclic voltammetry; detection limit; Electrochemical electrodes; electrochemistry; glucose; Gold; hydrogen peroxide; Laser-induced deposition; microstructure; Non-enzymatic sensors; scanning electron microscopy; topology; X-ray diffraction; Cyclic voltammetry; Gold; Non-enzymatic sensors; Laser-induced deposition; Copper; Electrochemical electrodes
• ISSN: 0039-9140; 1873-3573; 1873-3573
• DOI: 10.1016/j.talanta.2017.01.089

The synthesis of conductive gold and copper-gold microstructures with high developed surface based on the method of laser-induced metal deposition from solution was developed. The topology and crystallization phase of these structures were observed by means of scanning electron microscopy and X-ray diffraction, respectively. The electrochemical properties of the synthesized materials were investigated using cyclic voltamperometry and amperometry. According to the obtained results, it was found out that copper-gold microstructures demonstrate a linear dependence of Faraday current vs. concentration from 0.025 to 5µM for D-glucose and from 0.025 to 10µM for hydrogen peroxide. In turn, gold deposit exhibits a linear dependence of Faraday current vs. concentration from 0.025 to 50µM for D-glucose and from 0.025 to 1µM for hydrogen peroxide. Moreover, the synthesized materials reveal low detection limits (0.025µM) with respect to the aforementioned analytes, which is quite promising for their potential application in design and fabrication of new non-enzymatic biosensors. [Display omitted] •The method for synthesis of copper-gold and gold microelectrodes was proposed.•The produced conductive metal structures have highly developed surface area.•These structures reveal high selectivity towards D-glucose and hydrogen peroxide.•Copper-gold and gold electrodes exhibit rather good reproducibility and stability.