Impact of Age Matching of Donors to Recipients on Renal Transplant Outcomes Following Donation After Cardiac Death

• Published in: Transplantation proceedings Vol. 42; no. 10; pp. 3954 - 3956
• Main Authors: Pine, J.K, Ridgway, D.M, Goldsmith, P.J, Baker, R.J, Lewington, A.J, Menon, K.V, Ahmad, N, Attia, M
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier Inc 01.12.2010; Elsevier
• Subjects: Adult; Age Factors; Biological and medical sciences; Cohort Studies; Death; Female; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Humans; Kidney Transplantation; Male; Medical sciences; Middle Aged; Patient Selection; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue Donors; Tissue, organ and graft immunology; Heart; Suboptimal donor; Human; Prognosis; Mortality; Recipient; Transplantation; Homotransplantation; Kidney; Medicine; Treatment; Urinary system; Surgery; Donation; Evolution; Graft; Death; Circulatory system; Age
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2010.10.003

Abstract Organ donation after cardiac death (DCD) provides a valuable supply of grafts for renal transplantation. Age matching of donors to recipients is often used. We sought to determine the impact of age matching on the outcomes among our cohort of DCD renal transplant recipients. Using our institutional database, we gathered information on all DCD renal transplants performed between April 2002 and December 2009. We divided the cohort into two groups based upon the donor:recipient age ratio: age-matched (between 25th and 75th percentiles, n = 99) and non-age-matched (<25th percentile and >75th centile, n = 100). We failed to demonstrate any significant difference between the two groups in terms of early complications or long-term outcome or function. Age matching did not appear to affect graft outcomes, particularly for young donors, but may have a role in older donors.