Severe Rhabdomyolysis After Allogeneic Transplantation of Facial Structures: A Case Report

• Published in: Transplantation proceedings Vol. 42; no. 8; pp. 3081 - 3082
• Main Authors: Hinojosa Pérez, R, Porras López, M, Escoresca-Ortega, A.M, Herruzo Avilés, A, León, A, Noval, J.A, Gómez-Cía, T, Sicilia, D, González Padilla, J.D
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier Inc 01.10.2010; Elsevier
• Subjects: Adult; Biological and medical sciences; Body Mass Index; Face; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Humans; Male; Medical sciences; Rhabdomyolysis - etiology; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue, organ and graft immunology; Transplantation - adverse effects; Transplantation, Homologous; Human; Homograft; Transplantation; Rhabdomyolysis; Case study; Medicine; Striated muscle disease; Treatment; Allogeneic hematopoietic stem cell transplantation; Surgery; Graft; Face; Severe; Structure
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2010.08.007

Abstract We present a patient with panfacial neurofibromatosis type 1 who underwent allogeneic transplantation of facial structures, which was complicated by severe rhabdomyolysis and temporary oligoanuria. Because of his underlying disease, this 35 year-old man, weighing 68 kg and with a body mass index (BMI) of 27, had undergone 17 operations for resection modeling of hypertrophied tissues, either alone or combined with static suspension techniques. He finally underwent allogeneic transplantation of facial structures. In the early hours of the postoperative period, in the context of a systemic inflammatory response syndrome, he experienced severe rhabdomyolysis, with elevation of the muscle enzyme creatine kinase producing a minor impact on kidney function. The patient was discharged home at 12 weeks after the transplantation.