Synthesis of some new bis-Schiff bases of isatin and 5-fluoroisatin in a water suspension medium

Condensation of aromatic primary bis-amines with isatin (1H-indole-2,3-dione) and 5-flouroisatin occurred cleanly and efficiently in a water suspension medium without using any organic solvent or acid catalyst. The corresponding bis-Schiff bases were obtained in good yields and were easily isolated...

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Bibliographic Details
Published inMolecules (Basel, Switzerland) Vol. 11; no. 1; pp. 59 - 63
Main Authors Jarrahpour, A A, Khalili, D
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 31.01.2006
MDPI
Subjects
5-fluoroisatin
Acids
bis-Schiff bases
Chromatography
Isatin - analogs & derivatives
Isatin - chemical synthesis
isatn
Models, Biological
Schiff Bases - chemical synthesis
Solvents
Temperature
Water
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Summary:Condensation of aromatic primary bis-amines with isatin (1H-indole-2,3-dione) and 5-flouroisatin occurred cleanly and efficiently in a water suspension medium without using any organic solvent or acid catalyst. The corresponding bis-Schiff bases were obtained in good yields and were easily isolated by filtration. Their structures were confirmed by (1)H-NMR, (13)C-NMR, IR and mass spectra.
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ISSN:1420-3049
1420-3049
DOI:10.3390/11010059