Coherent spontaneous activity accounts for trial-to-trial variability in human evoked brain responses

• Published in: Nature neuroscience Vol. 9; no. 1; pp. 23 - 25
• Main Authors: Fox, Michael D, Snyder, Abraham Z, Zacks, Jeffrey M, Raichle, Marcus E
• Format: Journal Article
• Language: English
• Published: United States Nature Publishing Group 01.01.2006
• Subjects: Brain; Brain - physiology; Evoked Potentials - physiology; Humans; Magnetic Resonance Imaging; Medical examination; Oxygen - blood; Photic Stimulation; Physiological aspects; Psychomotor Performance - physiology; Reproducibility of Results; United States

Trial-to-trial variability in the blood oxygen level-dependent (BOLD) response of functional magnetic resonance imaging has been shown to be relevant to human perception and behavior, but the sources of this variability remain unknown. We demonstrate that coherent spontaneous fluctuations in human b...