A low molecular weight fucoidan fraction from the brown seaweed Pelvetia canaliculata

• Published in: Phytochemistry (Oxford) Vol. 35; no. 3; pp. 697 - 700
• Main Authors: Colliec, Sylvia, Boisson-vidal, Catherine, Jozefonvicz, Jacqueline
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 01.02.1994; Elsevier
• Subjects: anticoagulant; anticoagulants; Biological and medical sciences; brown seaweed; chemical constituents of plants; Chemical constitution; Fundamental and applied biological sciences. Psychology; General pharmacology; low molecular weight fucoidan; Marine; Medical sciences; medicinal plants; Pelvetia canaliculata; Phaeophyceae; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; physicochemical properties; Plant physiology and development; polysaccharides; sulphated polysaccharide; brown seaweed; low molecular weight fucoidan; anticoagulant; sulphated polysaccharide; Pelvetia canaliculata; Characterization; Sulfur compounds; Algae; Marine plant; Isolation; Anticoagulant; Polysaccharide; Biological activity; Molecular weight; Phaeophycophyta; Thallophyta
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/S0031-9422(00)90590-9

A homogeneous highly purified fucoidan fraction (F2) with a low molecular weight was obtained by hydrolysis of crude fucoidan extracted from the brown seaweed Pelvetia canaliculata. Moreover, this fraction exhibited anticoagulant properties, and with both low viscosity and low molecular weight compatible with further in vivo experiments and clinical use, could be a promising anticoagulant agent.