Participation of μ-calpain in status epilepticus-induced hippocampal injury

• Published in: Brain research bulletin Vol. 78; no. 4; p. 131
• Main Authors: Lopez-Meraz, Maria-Leonor, Niquet, Jerome
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 16.03.2009
• Subjects: Animals; Antipsychotic Agents - administration & dosage; Antipsychotic Agents - toxicity; Apoptosis - drug effects; Apoptosis Inducing Factor - metabolism; BH3 Interacting Domain Death Agonist Protein - metabolism; Calpain; Calpain - antagonists & inhibitors; Calpain - metabolism; Caspase 3 - metabolism; Caspase-3; Cysteine Proteinase Inhibitors - pharmacology; Cytochromes c - secretion; Dipeptides - pharmacology; Enzyme Activation - drug effects; Hippocampus - metabolism; Hippocampus - pathology; Lithium Compounds - administration & dosage; Lithium Compounds - toxicity; Mitochondria - drug effects; Mitochondria - metabolism; Muscarinic Agonists - administration & dosage; Muscarinic Agonists - toxicity; Neurology; Neuronal damage; Neurons - drug effects; Neurons - metabolism; Neurons - pathology; Pilocarpine; Pilocarpine - administration & dosage; Pilocarpine - toxicity; Rats; Spectrin - metabolism; Status epilepticus; Status Epilepticus - chemically induced; Status Epilepticus - metabolism; Status Epilepticus - physiopathology; Calpain; Neuronal damage; Pilocarpine; Status epilepticus; Caspase-3
• ISSN: 0361-9230; 1873-2747
• DOI: 10.1016/j.brainresbull.2008.11.002

Abstract We comment this manuscript recently published in Brain Res. Bull.: S. Wang, S. Wang, P. Shan, Z. Song, T. Dai, R. Wang, Z. Chi, Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus. Brain Res. Bull. 76(1–2) (2008) 90–96.