Arterial hypertension and cognitive dysfunction in physiologic and pathologic aging of the brain

Arterial hypertension is the most important modifiable cerebrovascular risk factor; its relationship with cerebrovascular disease is continuous, consistent, and independent. Different and probably converging pathophysiologic mechanisms explain the role of arterial hypertension in causing cognitive d...

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Published inThe American journal of geriatric cardiology Vol. 16; no. 3; p. 158
Main Authors Lanari, Alessia, Silvestrelli, Giorgio, De Dominicis, Pierangelo, Tomassoni, Daniele, Amenta, Francesco, Parnetti, Lucilla
Format Journal Article
LanguageEnglish
Published United States 01.05.2007
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Summary:Arterial hypertension is the most important modifiable cerebrovascular risk factor; its relationship with cerebrovascular disease is continuous, consistent, and independent. Different and probably converging pathophysiologic mechanisms explain the role of arterial hypertension in causing cognitive dysfunction in pathologic aging of the brain, specifically, vascular dementia and Alzheimer's disease.
ISSN:1076-7460
DOI:10.1111/j.1076-7460.2007.06502.x