Evaluation of carotid artery elasticity in patients with uremia by echo tracking

• Published in: Journal of medical ultrasonics (2001) Vol. 45; no. 4; pp. 591 - 596
• Main Authors: Liang, Hong, Wang, Dawei, Che, Guoying, Su, Yanxin
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.10.2018; Springer; Springer Nature B.V
• Subjects: Adult; Analysis; Apolipoproteins; Arteriosclerosis; Atherosclerosis; Blood pressure; Care and treatment; Carotid arteries; Carotid Arteries - diagnostic imaging; Carotid Arteries - physiology; Carotid Intima-Media Thickness; Diabetes; Disease; Elastic Modulus; Elasticity Imaging Techniques; Female; High density lipoprotein; Humans; Hypertension; Imaging; Kidney diseases; Lipoproteins; Male; Medicine; Medicine & Public Health; Middle Aged; Modulus of elasticity; Original Article; Patients; Radiology; Reproducibility; Reproducibility of Results; Strain; Thickness measurement; Tracking control; Ultrasound; Ultrasound imaging; Uremia; Uremia - diagnostic imaging; Uremia - physiopathology; User-Computer Interface; Veins & arteries; Wave velocity; Young Adult; Elasticity; Uremia; Carotid; Echo tracking; Intima–media thickness
• ISSN: 1346-4523; 1613-2254; 1613-2254
• DOI: 10.1007/s10396-018-0868-z

Purpose The purpose of this study was to compare the carotid artery wall elasticity between patients with uremia and controls using echo tracking (ET). Methods Ninety-three patients with uremia and 35 control subjects (Group A) were enrolled in this study. In the ET mode, the carotid artery elasticity parameters including stiffness index ( β ), pressure–strain elasticity modulus (EP), arterial compliance (AC), and one-point pulse wave velocity (PWVβ) were measured, and carotid intima–media thickness (IMT) was measured with B-mode ultrasonography. The patients were classified into three groups: Group B (normal IMT), Group C (thickened IMT), and Group D (one single atheroma plaque). Results β , EP, and PWVβ were significantly higher in Group B, C, and D (especially in group D) than those of the control group ( P  < 0.05), and there were significant differences between Group A and Group B, while AC was lower than in controls, but there were no statistically significant differences among the four groups. Conclusions ET is a noninvasive method that can demonstrate a loss in carotid artery elasticity in uremia patients with normal IMT.