Late Renal Vein Thrombosis Associated With Recurrence of Membranous Nephropathy in a Renal Allograft: A Case Report

• Published in: Transplantation proceedings Vol. 40; no. 9; pp. 3259 - 3260
• Main Authors: Carrasco, A, Díaz, C, Flores, J.C, Briones, E, Otipka, N
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier Inc 01.11.2008; Elsevier
• Subjects: Anticoagulants - therapeutic use; Biological and medical sciences; Blood and lymphatic vessels; Cadaver; Cardiology. Vascular system; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Glomerulonephritis, Membranous - drug therapy; Glomerulonephritis, Membranous - pathology; Heparin - therapeutic use; Humans; Kidney Transplantation - pathology; Male; Medical sciences; Middle Aged; Oliguria - drug therapy; Renal Veins - pathology; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue Donors; Tissue, organ and graft immunology; Transplantation, Homologous - pathology; Treatment Outcome; Venous Thrombosis - drug therapy; Venous Thrombosis - pathology; Kidney disease; Human; Relapse; Late; Urinary system disease; Renal vein; Cardiovascular disease; Transplantation; Homotransplantation; Kidney; Venous disease; Vascular disease; Case study; Medicine; Association; Treatment; Urinary system; Surgery; Graft; Membranous glomerulonephritis; Venous thrombosis
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2008.03.122

Abstract Allograft renal vein thrombosis (RVT) is an uncommon but potentially catastrophic complication. Although it usually occurs in the early posttransplant period and is associated with surgical complications or vascular rejection, it may develop later, when it is generally related with a hypercoagulable state. Typical clinical presentation is sudden oligoanuric acute renal failure, and hematuria, with a painful and swollen renal allograft. Confirmation of the diagnosis requires Doppler ultrasound and computed tomography. Herein we have reported a successfully treated case of late RVT that developed in an allograft with recurrent membranous nephropathy associated with the nephrotic syndrome. The patient fully recovered renal graft function a few days after presentation, which was related to anticoagulant therapy. We demonstrated complete recanalization of the venous thrombosis.