Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

• Published in: Scientific data Vol. 5; no. 1; p. 180160
• Main Authors: He, Liqun, Vanlandewijck, Michael, Mäe, Maarja Andaloussi, Andrae, Johanna, Ando, Koji, Del Gaudio, Francesca, Nahar, Khayrun, Lebouvier, Thibaud, Laviña, Bàrbara, Gouveia, Leonor, Sun, Ying, Raschperger, Elisabeth, Segerstolpe, Åsa, Liu, Jianping, Gustafsson, Sonja, Räsänen, Markus, Zarb, Yvette, Mochizuki, Naoki, Keller, Annika, Lendahl, Urban, Betsholtz, Christer
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.08.2018; Nature Publishing Group
• Subjects: 631/1647/2017; 631/1647/334/1874/345; 631/1647/514/1949; 631/378/340; Animals; Blood vessels; Blood Vessels - cytology; Blood Vessels - physiology; Brain - blood supply; Data Descriptor; Databases, Factual; Datasets; Endothelial Cells - physiology; Gene expression; Humanities and Social Sciences; Lung - blood supply; Lungs; Mice; multidisciplinary; Myocytes, Smooth Muscle - physiology; Pericytes - physiology; Ribonucleic acid; RNA; Rodents; Science; Sequence Analysis, RNA; Single-Cell Analysis; Structure-function relationships; Transcriptome; Vascular diseases

Vascular diseases are major causes of death, yet our understanding of the cellular constituents of blood vessels, including how differences in their gene expression profiles create diversity in vascular structure and function, is limited. In this paper, we describe a single-cell RNA sequencing (scRN...