Elevated blood lead levels in children are associated with lower erythropoietin concentrations

• Published in: The Journal of pediatrics Vol. 134; no. 1; pp. 107 - 109
• Main Authors: Liebelt, Erica L., Schonfeld, David J., Gallagher, Patrick
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 1999; Elsevier; Mosby-Year Book, Inc
• Subjects: Analysis of Variance; Anemias. Hemoglobinopathies; Biological and medical sciences; Child; Child, Preschool; Diseases of red blood cells; Enzyme Inhibitors - blood; Enzyme-Linked Immunosorbent Assay; Erythropoietin - blood; Female; Hematologic and hematopoietic diseases; Humans; Infant; Lead - blood; Male; Medical sciences; Pilot Projects; Protoporphyrins - blood; BPb; EPO; Human; Concentration factor; Erythropoietin; Pathophysiology; Anemia; Lead; Hemopathy; Poisoning; Glycoprotein hormone; Child

Eighty-six children (mean age, 34 months) were studied to determine whether elevated blood lead levels in children are associated with lower erythropoietin concentrations. The median erythropoietin concentration was 5.9 mIU/mL (range, 2.3 to 11.5 mIU/mL), and the median blood lead level was 0.87 μmo...