NAD + Repletion Reverses Heart Failure With Preserved Ejection Fraction

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Bibliographic Details
Published inCirculation research Vol. 128; no. 11; pp. 1629 - 1641
Main Authors Tong, Dan, Schiattarella, Gabriele G, Jiang, Nan, Altamirano, Francisco, Szweda, Pamela A, Elnwasany, Abdallah, Lee, Dong I, Yoo, Heesoo, Kass, David A, Szweda, Luke I, Lavandero, Sergio, Verdin, Eric, Gillette, Thomas G, Hill, Joseph A
Format Journal Article
LanguageEnglish
Published United States 28.05.2021
Subjects
Acetylation
Acyl-CoA Dehydrogenase - metabolism
Animals
Disease Models, Animal
Down-Regulation
Fatty Acids - metabolism
Heart Failure, Diastolic - therapy
Humans
Ketone Oxidoreductases - metabolism
Male
Mice
Mice, Inbred C57BL
Mitochondria, Heart - metabolism
Mitochondrial Myopathies - metabolism
Mitochondrial Myopathies - therapy
NAD - analysis
NAD - biosynthesis
NAD - deficiency
NAD - genetics
Niacinamide - administration & dosage
Niacinamide - analogs & derivatives
Oxidation-Reduction
Oxygen Consumption
Pyridinium Compounds - administration & dosage
Sirtuin 3 - metabolism
NAD
acetylation
heart failure
cardiomyopathy
mitochondria
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Summary:[Figure: see text].
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0009-7330
1524-4571
1524-4571
DOI:10.1161/CIRCRESAHA.120.317046