Characterization of two putative fibronectin-binding proteins of Clostridium perfringens

• Published in: Anaerobe Vol. 15; no. 4; pp. 155 - 159
• Main Authors: Katayama, Seiichi, Nozu, Nanami, Okuda, Masaya, Hirota, Shinsuke, Yamasaki, Tsutomu, Hitsumoto, Yasuo
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2009
• Subjects: Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Chromatography; Cloning, Molecular; Clostridium perfringens; Clostridium perfringens - genetics; Clostridium perfringens - growth & development; Clostridium perfringens - isolation & purification; Clostridium perfringens - metabolism; Enzyme-Linked Immunosorbent Assay; Fibronectin; Fibronectin-binding protein; Fibronectins - metabolism; Gas gangrene; Gas Gangrene - microbiology; Gene Expression Regulation, Bacterial; Humans; Polymerase Chain Reaction; Protein Binding; Recombinant Proteins - genetics; Recombinant Proteins - metabolism; Fibronectin-binding protein; Clostridium perfringens; Fibronectin; Gas gangrene

Clostridium perfringens is a Gram-positive anaerobic pathogen that causes gas gangrene and food poisoning in humans and animals. Genomic analysis of C. perfringens strain 13 revealed that this bacterium contains two genes (CPE0737 and CPE1847) that encode putative fibronectin (Fn)-binding proteins (...