Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery

• Published in: Chemical science (Cambridge) Vol. 8; no. 5; pp. 3489 - 3493
• Main Authors: Sun, Yao, Ding, Mingmin, Zeng, Xiaodong, Xiao, Yuling, Wu, Huaping, Zhou, Hui, Ding, Bingbing, Qu, Chunrong, Hou, Wei, Er-bu, A. G. A., Zhang, Yejun, Cheng, Zhen, Hong, Xuechuan
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 01.05.2017
• Subjects: Backbone; Biocompatibility; Chemistry; Chemistry, Multidisciplinary; Fluorescence; Imaging; Lymph; Mice; Physical Sciences; Science & Technology; Surgery; Tumors; AG2S QUANTUM DOTS; REAL-TIME VISUALIZATION; METASTASIS; FLUORESCENCE; LIGHT; DISEASE-FREE SURVIVAL; COMPLETE RESECTION; CANCER; MOUSE MODELS; BRAIN

Though high brightness and biocompatible small NIR-II dyes are highly desirable in clinical or translational cancer research, their fluorescent cores are relatively limited and their synthetic processes are somewhat complicated. Herein, we have explored the design and synthesis of novel NIR-II fluor...