Influence of the postoperative period and surgical procedure on ambulatory blood pressure-determination of hypertension load after successful surgical repair of coarctation of the aorta

• Published in: European heart journal Vol. 19; no. 4; pp. 638 - 646
• Main Authors: Johnson, D., Perrault, H., Vobecky, S.J., Fournier, A., Davignon, A.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.04.1998
• Subjects: Adolescent; Adult; ambulatory blood pressure; Analysis of Variance; Aortic Coarctation - surgery; Biological and medical sciences; Blood and lymphatic vessels; Blood Pressure Monitoring, Ambulatory; Cardiology. Vascular system; Cardiovascular Surgical Procedures - adverse effects; Circadian Rhythm; coarctation of the aorta; Diseases of the aorta; Female; Follow-Up Studies; Humans; hypertension; Hypertension - diagnosis; Hypertension - epidemiology; Hypertension - etiology; Hypertension - physiopathology; Male; Medical sciences; Postoperative Period; Prevalence; Prognosis; Reference Values; Time Factors; Human; Hypertension; Aortic coarctation; Prognosis; Cardiovascular disease; Congenital disease; Vascular disease; Treatment; Malformation; Surgery; Arterial pressure; Ambulatory; Technique; Aortic disease; Monitoring
• ISSN: 0195-668X; 1522-9645
• DOI: 10.1053/euhj.1997.0804

Aims This study quantified hypertension load using 24-h ambulatory blood pressure monitoring after successful repair of coarctation of the aorta less than (1) or more than 10 years previously (2) and examined the influence of the surgical procedure (anastomosis or subclavian flap). Methods and Results Ambulatory blood pressure recordings were obtained using an Accutracker II monitor every 30min during the day and hourly, at night. Day and night systolic and diastolic values were higher in coarctation of the aorta than in controls: (day: systolic blood pressure/diastolic blood pressure: 133/71±6/4 vs 115/66±3/2 night: systolic blood pressure/diastolic blood pressure: 117/61±4/4 vs 107/57±3/2mmHg, P<0·01) and at all times, were higher in coarctation of the aorta (2) than in coarctation of the aorta (1). Clinical daytime systolic hypertension was observed in 20% of recordings from coarctation of the aorta (1) and 49% from coarctation of the aorta (2) while diastolic hypertension was not observed. However, systolic blood pressure and diastolic blood pressure responses to daily activities were significantly higher in coarctation of the aorta than in controls and this was more marked in coarctation of the aorta (2) than in coarctation of the aorta (1). Type of surgery did not affect either hypertension prevalence or blood pressure reactivity. Conclusions These observations indicate exaggerated systolic blood pressure and diastolic blood pressure reactivity after repair of coarctation of the aorta, the prevalence of systolic hypertension doubling 10 years after surgery.