Neuromechanical control of impact absorption during induced lower limb loading in individuals post-stroke

• Published in: Scientific reports Vol. 12; no. 1; p. 19104
• Main Authors: Shen, Keng-Hung, Prajapati, Sunil K., Borrelli, James, Gray, Vicki L., Westlake, Kelly P., Rogers, Mark W., Hsiao, Hao-Yuan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 09.11.2022; Nature Portfolio
• Subjects: 692/308; 692/617; 692/700; Ankle Joint; Biomechanical Phenomena - physiology; Gait - physiology; Humanities and Social Sciences; Humans; Lower Extremity; multidisciplinary; Science; Science (multidisciplinary); Stroke - complications; Stroke Rehabilitation - methods; Walking - physiology
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-21271-8

Decreased loading of the paretic lower limb and impaired weight transfer between limbs negatively impact balance control and forward progression during gait in individuals post-stroke. However, the biomechanical and neuromuscular control mechanisms underlying such impaired limb loading remain unclear, partly due to their tendency of avoiding bearing weight on the paretic limb during voluntary movement. Thus, an approach that forces individuals to more fully and rapidly load the paretic limb has been developed. The primary purpose of this study was to compare the neuromechanical responses at the ankle and knee during externally induced limb loading in people with chronic stroke versus able-bodied controls, and determine whether energy absorption capacity, measured during induced limb loading of the paretic limb, was associated with walking characteristics in individuals post-stroke. Results revealed reduced rate of energy absorption and dorsiflexion velocity at the ankle joint during induced limb loading in both the paretic and non-paretic side in individuals post-stroke compared to healthy controls. The co-contraction index was higher in the paretic ankle and knee joints compared to the non-paretic side. In addition, the rate of energy absorption at the paretic ankle joint during the induced limb loading was positively correlated with maximum walking speed and negatively correlated with double limb support duration. These findings demonstrated that deficits in ankle dorsiflexion velocity may limit the mechanical energy absorption capacity of the joint and thereby affect the lower limb loading process during gait following stroke.