Primary cutaneous carcinosarcoma: Dermoscopic and immunohistochemical features

ABSTRACT A 73‐year‐old man presented a 9‐month history of an enlarging nodule on his right temple. Dermoscopy revealed a non‐pigmented lesion with ulceration, fibrosis and pale globules. An excisional biopsy was carried out and histology showed a biphasic tumour with a basal cell carcinoma like epit...

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Bibliographic Details
Published inAustralasian journal of dermatology Vol. 51; no. 1; pp. 26 - 28
Main Authors Upjohn, Edward, Braue, Anna, Ryan, Andrew
Format Journal Article
LanguageEnglish
Published Melbourne, Australia Blackwell Publishing Asia 01.02.2010
Wiley-Blackwell
Subjects
Aged
Australia
Biological and medical sciences
Carcinoma, Basal Cell - diagnosis
Carcinoma, Basal Cell - pathology
Carcinoma, Basal Cell - surgery
Carcinosarcoma - diagnosis
Carcinosarcoma - pathology
Carcinosarcoma - surgery
Dermatology
Dermoscopy
Giant Cells - pathology
Humans
Immunohistochemistry
Male
Medical sciences
Osteoclasts - pathology
primary cutaneous carcinosarcoma
Skin Neoplasms - diagnosis
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Australia
Immunohistochemistry
primary cutaneous carcinosarcoma
Anatomic pathology
Dermatology
Skin
Malignant tumor
Cancer
Spindle cell carcinoma
dermoscopy
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Summary:ABSTRACT A 73‐year‐old man presented a 9‐month history of an enlarging nodule on his right temple. Dermoscopy revealed a non‐pigmented lesion with ulceration, fibrosis and pale globules. An excisional biopsy was carried out and histology showed a biphasic tumour with a basal cell carcinoma like epithelial component and a dermal undifferentiated sarcoma, with pleomorphic spindle cells and numerous osteoclast‐like giant cells. Based on immunohistochemistry findings, a diagnosis of primary cutaneous carcinosarcoma was made and the patient underwent wide local excision.
Bibliography:Edward Upjohn, MB BS FACD. Anna Braue, MBBS MMed. Andrew Ryan MBBS, FRCPA.
ObjectType-Case Study-2
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ObjectType-Report-1
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ISSN:0004-8380
1440-0960
DOI:10.1111/j.1440-0960.2009.00587.x