Robotic‐assisted versus open radical cystectomy in bladder cancer: A meta‐analysis of four randomized controlled trails
Background Robot‐assisted radical cystectomy (RARC) is increasing annually for treatment of bladder cancer. The objective of this meta‐analysis was to compare the safety and efficacy of RARC and open radical cystectomy (ORC) for bladder cancer. Methods Our meta‐analysis searches were conducted using...
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Published in | The international journal of medical robotics + computer assisted surgery Vol. 14; no. 1 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
Wiley Subscription Services, Inc
01.02.2018
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Subjects | |
Online Access | Get full text |
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Summary: | Background
Robot‐assisted radical cystectomy (RARC) is increasing annually for treatment of bladder cancer. The objective of this meta‐analysis was to compare the safety and efficacy of RARC and open radical cystectomy (ORC) for bladder cancer.
Methods
Our meta‐analysis searches were conducted using PubMed, Web of Science, and Cochrane Library databases to identify randomized controlled trials (RCT) assessing the two techniques.
Results
Four RCT studies were identified, including 239 cases. Our studies indicated that RARC was associated with longer operative time (WMD: 69.69, 95% CI:17.25 to122.12; P= 0.009), lower estimated blood loss (WMD: –299.83, 95% CI:–414.66to −184.99; P<0.00001). The two groups had no significant difference in overall perioperative complications, length of hospital stay, lymph node yield and positive surgical margins.
Conclusions
RARC is mini‐invasive alternative to ORC for bladder cancer. The advantage of RARC was reduced estimated blood loss. More studies are needed to compare the two techniques. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 1478-5951 1478-596X |
DOI: | 10.1002/rcs.1867 |