Guidelines for establishing locus specific databases

• Published in: Human mutation Vol. 33; no. 2; pp. 298 - 305
• Main Authors: Vihinen, Mauno, den Dunnen, Johan T., Dalgleish, Raymond, Cotton, Richard G. H.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.02.2012; Hindawi Limited
• Subjects: Computational Biology - methods; Computational Biology - standards; data collection; Database Management Systems; Databases, Genetic - ethics; Databases, Genetic - standards; distribution; Documentation; Genes; Genetic Association Studies; Genetic Loci; guidelines; Guidelines as Topic; Humans; Information Dissemination; LSDB; variation database curation

Information about genetic variation has been collected for some 20 years into registries, known as locus specific databases (LSDBs), which nowadays often contain information in addition to the actual genetic variation. Several issues have to be taken into account when considering establishing and ma...