Anatomical Differences Between Human and Pig Hearts and Their Relevance for Cardiac Xenotransplantation Surgical Technique

Cardiac xenotransplantation has been proposed to bridge the gap between supply and demand for patients with end-stage heart failure requiring transplantation. However, differences in pig anatomy compared with human anatomy require modification of the surgical approach. In addition, careful considera...

Full description

Saved in:
Bibliographic Details
Published inJACC. Case reports Vol. 4; no. 16; pp. 1049 - 1052
Main Authors Shah, Aakash, Goerlich, Corbin E., Pasrija, Chetan, Hirsch, Jeffrey, Fisher, Stacy, Odonkor, Patrick, Strauss, Erik, Ayares, David, Mohiuddin, Muhammad M., Griffith, Bartley P.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 17.08.2022
Elsevier
Subjects
cardiac transplantation
Cardiovascular
Case Report
chronic heart failure
genetic engineering
CT
PA
SVC
cardiac transplantation
IVC
chronic heart failure
genetic engineering
GHRKO
RA
computed tomography
pulmonary artery
growth hormone receptor knockout
inferior vena cava
right atrium
superior vena cava
Online AccessGet full text
ISSN2666-0849
2666-0849
DOI10.1016/j.jaccas.2022.06.011

Cover

More Information
Summary:Cardiac xenotransplantation has been proposed to bridge the gap between supply and demand for patients with end-stage heart failure requiring transplantation. However, differences in pig anatomy compared with human anatomy require modification of the surgical approach. In addition, careful consideration should be given to size matching before transplantation. (Level of Difficulty: Advanced.) [Display omitted]
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:2666-0849
2666-0849
DOI:10.1016/j.jaccas.2022.06.011