Proteins involved in building, maintaining and remodeling of yeast cell walls

• Published in: Current genetics Vol. 59; no. 4; pp. 171 - 185
• Main Authors: Teparic, R, Mrsa, Vladimir
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.11.2013; Springer Berlin Heidelberg; Springer Nature B.V
• Subjects: Amino Acid Sequence; Biochemistry; Biomedical and Life Sciences; Biosynthetic Pathways; Biosynthetic Pathways - physiology; Cell Biology; Cell Wall; Cell Wall - metabolism; Cell Wall - physiology; cell walls; Chitin; Chitin Synthase; Chitin Synthase - metabolism; firmness; Fungal Polysaccharides; Fungal Polysaccharides - metabolism; Fungal Proteins; Fungal Proteins - genetics; Fungal Proteins - metabolism; genetics; Glucans; Glucans - metabolism; Glucosyltransferases; Glucosyltransferases - metabolism; hydrolases; Life Sciences; Membrane Glycoproteins; Membrane Glycoproteins - metabolism; metabolism; Microbial Genetics and Genomics; Microbiology; Models, Biological; Molecular Sequence Data; physiology; Plant Sciences; Proprotein Convertases; Proprotein Convertases - metabolism; proteins; Proteomics; Research Article; Saccharomyces cerevisiae Proteins; Saccharomyces cerevisiae Proteins - metabolism; Species Specificity; Yeasts; Yeasts - metabolism; Yeast cell walls; Chitin synthases; Cell wall proteins; Glucanases; Transglycosidases; Glucan synthases
• ISSN: 0172-8083; 1432-0983; 1432-0983
• DOI: 10.1007/s00294-013-0403-0

The cell wall defines the shape and provides osmotic stability to the yeast cell. It also serves to anchor proteins required for communication of the yeast cell with surrounding molecules and other cells. It is synthesized as a complex structure with β-1,3-glucan chains forming the basic network to which β-1,6-glucan, chitin and a number of mannoproteins are attached. Synthesis, maintaining and remodeling of this complex structure require a set of different synthases, hydrolases and transglycosidases whose concerted activities provide necessary firmness but at the same time flexibility of the wall moiety. The present state of comprehension of the interplay of these proteins in the yeast cell wall is the subject of this article.