The Influence of Multimorbidity on Leading Causes of Death in Older Adults With Cognitive Impairment

Objective: The aim of this study is to evaluate the relationship of leading causes of death with gradients of cognitive impairment and multimorbidity. Method: This is a population-based study using data from the linked 1992-2010 Health and Retirement Study and National Death Index (n = 9,691). Multi...

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Published inJournal of aging and health Vol. 31; no. 6; pp. 1025 - 1042
Main Authors Schiltz, Nicholas K., Warner, David F., Sun, Jiayang, Smyth, Kathleen A., Gravenstein, Stefan, Stange, Kurt C., Koroukian, Siran M.
Format Journal Article
LanguageEnglish
Published Los Angeles, CA SAGE Publications 01.07.2019
SAGE PUBLICATIONS, INC
Subjects
Aged
Aged, 80 and over
Cause of Death - trends
Chronic Disease
Cognitive ability
Cognitive Dysfunction - epidemiology
Comorbidity
Female
Geriatric Assessment - methods
Geriatrics
Humans
Male
Middle Aged
Multimorbidity - trends
Retrospective Studies
Survival Rate - trends
United States - epidemiology
United States
mortality
cognitive status
cause of death
comorbidity
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Summary:Objective: The aim of this study is to evaluate the relationship of leading causes of death with gradients of cognitive impairment and multimorbidity. Method: This is a population-based study using data from the linked 1992-2010 Health and Retirement Study and National Death Index (n = 9,691). Multimorbidity is defined as a combination of chronic conditions, functional limitations, and geriatric syndromes. Regression trees and Random Forest identified which combinations of multimorbidity associated with causes of death. Results: Multimorbidity is common in the study population. Heart disease is the leading cause in all groups, but with a larger percentage of deaths in the mild and moderate/severe cognitively impaired groups than among the noncognitively impaired. The different “paths” down the regression trees show that the distribution of causes of death changes with different combinations of multimorbidity. Discussion: Understanding the considerable heterogeneity in chronic conditions, functional limitations, geriatric syndromes, and causes of death among people with cognitive impairment can target care management and resource allocation.
Bibliography:ObjectType-Article-1
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ISSN:0898-2643
1552-6887
DOI:10.1177/0898264317751946