Enriched fluoridation of octacalcium phosphate by ionic liquid treatment

[Display omitted] Octacalcium phosphate (OCP) has attracted attention as a bone-repairing material with excellent bone regeneration ability, and F− incorporation is expected to further promote bone formation. However, because OCP is easily converted to fluorapatite in an aqueous fluoride solution, i...

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Bibliographic Details
Published inMaterials letters. X Vol. 15; p. 100151
Main Authors Miyazaki, Toshiki, Higa, Youta
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.09.2022
Elsevier
Subjects
1-ethyl-3-methylimidazolium tetrafluoroborate
Chemical durability
Fluoridation
Ionic liquid
Octacalcium phosphate
1-ethyl-3-methylimidazolium tetrafluoroborate
Fluoridation
Octacalcium phosphate
Chemical durability
Ionic liquid
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Summary:[Display omitted] Octacalcium phosphate (OCP) has attracted attention as a bone-repairing material with excellent bone regeneration ability, and F− incorporation is expected to further promote bone formation. However, because OCP is easily converted to fluorapatite in an aqueous fluoride solution, it is difficult to incorporate a large amount of F− while maintaining the crystalline structure of OCP. Therefore, in this study, we attempted to introduce F− into OCP using an ionic liquid with high F− concentration in a non-aqueous environment. OCP was incorporated with F− in the form of ion pairs after treatment with an acetone solution of 1-ethyl-3-methylimidazolium tetrafluoroborate. The F− content was approximately 9%, which was approximately 28 times greater than achieved in previous studies. The amount of OCP with F− dissolved in acetate buffer was less than that of untreated OCP.
ISSN:2590-1508
2590-1508
DOI:10.1016/j.mlblux.2022.100151