Babesia divergens vaccine

A vaccine strategy against Babesia divergens bovine babesiosis was successfully developed after perfecting of an efficient in vitro culture. Crude supernatants and purified fractions were able to induce a vaccine protection in gerbils against B. divergens infection. More, supernatants induced an eff...

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Published inMemórias do Instituto Oswaldo Cruz Vol. 87 Suppl 3; no. suppl 3; pp. 279 - 281
Main Authors Gorenflot, A, Precigout, E, Valentin, A, Bissuel, G, Carcy, B, Brasseur, P, Moreau, Y, Schrevel, J
Format Journal Article
LanguageEnglish
Portuguese
Published Brazil Instituto Oswaldo Cruz, Ministério da Saúde 1992
Fundação Oswaldo Cruz (FIOCRUZ)
Subjects
Animals
Antigens, Protozoan - immunology
Babesia - immunology
Babesia divergens
Babesiosis - immunology
Babesiosis - prevention & control
Cattle
Cattle Diseases - immunology
Cattle Diseases - prevention & control
exoatingen
Gerbillinae
in vitro culture
PARASITOLOGY
Parasitology - methods
Protozoan Vaccines
TROPICAL MEDICINE
Vaccination
vaccine
vaccine
exoatingen
Babesia divergens
in vitro culture
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Summary:A vaccine strategy against Babesia divergens bovine babesiosis was successfully developed after perfecting of an efficient in vitro culture. Crude supernatants and purified fractions were able to induce a vaccine protection in gerbils against B. divergens infection. More, supernatants induced an effective vaccine protection in cattle. The role of B. divergens exoantigens of 17, 37, 46, 70 and 90 kDa in the development of the immune response was clearly demonstrated in gerbils, cattle, and man.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0074-0276
1678-8060
0074-0276
1678-8060
DOI:10.1590/S0074-02761992000700047