Modification of Cotton Fabric with Molecularly Imprinted Polymer-Coated Carbon Dots as a Sensor for 17 α-methyltestosterone

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 21; p. 7257
• Main Authors: Lim, Monyratanak, Thanasupsin, Sudtida Pliankarom, Thongkon, Nisakorn
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 26.10.2022; MDPI
• Subjects: 17 α-methyltestosterone; Aquaculture; Azobisisobutyronitrile; Bisphenol A; Carbon; Carbon dots; Cellulose; Chromatography; Cotton; cotton fabric; Cotton fabrics; Endocrine disruptors; Ethylenediamine; Fabrics; Fluorescence; fluorescence image; Glycol dimethacrylates; Hormones; Image analysis; Image processing; Imprinted polymers; Laboratories; Mass spectrometry; Methacrylic acid; Methyltestosterone; Molecular Imprinting - methods; Molecularly Imprinted Polymers; Nanomaterials; PCB; Pesticides; Polychlorinated biphenyls; Polymer coatings; Polymer industry; Polymerization; Polymers; Scientific imaging; Sediment samplers; Sensors; smartphone detection; Smartphones; Steroids; Textile composites; Textile fabrics; Tilapia; Toiletries industry; Thailand; cotton fabric; carbon dots; fluorescence image; smartphone detection; 17 α-methyltestosterone; molecularly imprinted polymers
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules27217257

Molecularly imprinted polymers@ethylenediamine-modified carbon dots grafted on cotton fabrics (MIPs@EDA-CDs/CF) and smartphone-based fluorescence image analysis were proposed and used for the first time for the detection of 17 α-methyltestosterone (MT). The EDA-CDs were synthesized and grafted on cotton fabric before coating with the MIPs. The MIPs were synthesized using the MT as a template molecule, methacrylic acid (MAA) as a functional monomer, ethylene glycol dimethacrylate (EGDMA) as a cross-linker, and azobisisobutyronitrile (AIBN) as an initiator. The MIPs@EDA-CDs/CF were characterized using FTIR, SEM-EDS, and RGB fluorescence imaging. The fluorescence images were also taken using a smartphone and the ImageJ program was used for RGB measurement. The Δ red intensity was linearly proportional to MT concentration in the range of 100 to 1000 μg/L (R = 0.999) with a detection limit of 44.4 μg/L and quantification limit of 134 μg/L. The MIPs@EDA-CDs/CF could be stored at 4 °C for a few weeks and could be reused twice. The proposed method could apply for the specific determination of MT in water and sediment samples along with satisfactory recoveries of 96-104% and an acceptable relative standard deviation of 1-6% at the ppb level.