Integrated analysis reveals effects of bioactive ingredients from Limonium Sinense (Girard) Kuntze on hypoxia-inducible factor (HIF) activation

• Published in: Frontiers in plant science Vol. 13; p. 994036
• Main Authors: Zhao, Hualong, Wang, Siyuan, Zhou, Yilu, Ertay, Ayse, Williamson, Philip T. F., Ewing, Rob M., Tang, Xinhui, Wang, Jialian, Wang, Yihua
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 27.10.2022
• Subjects: cell cycle; cell viability; gallic acid; hypoxia-inducible factor; Limonium Sinense (Girard) Kuntze; Plant Science; Limonium Sinense (Girard) Kuntze; hypoxia-inducible factor; cell viability; cell cycle; gallic acid

Limonium Sinense (Girard) Kuntze is a traditional Chinese medicinal herb, showing blood replenishment, anti-tumour, anti-hepatitis, and immunomodulation activities amongst others. However, the mechanism of its pharmacological activities remains largely unknown. Here, we investigated the effects of b...