Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson's Disease

Parkinson's disease (PD) affects at least 10 million people worldwide. It is a neurodegenerative disease, which is currently diagnosed by neurological examination. No neuroimaging investigation or blood biomarker is available to aid diagnosis and prognosis. Most effort toward diagnosis using ma...

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Published inFrontiers in neurology Vol. 6; p. 146
Main Authors de Celis Alonso, Benito, Hidalgo-Tobón, Silvia S, Menéndez-González, Manuel, Salas-Pacheco, José, Arias-Carrión, Oscar
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 03.07.2015
Subjects
Diffusion MRI Tractography
MRI and fMRI
Neuroimaging (anatomic and functional)
Neuroscience
Parkinson’s disease (PD)
TMS
diffusion MRI
TMS
MRI
Parkinson’s disease
neuroimaging
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Summary:Parkinson's disease (PD) affects at least 10 million people worldwide. It is a neurodegenerative disease, which is currently diagnosed by neurological examination. No neuroimaging investigation or blood biomarker is available to aid diagnosis and prognosis. Most effort toward diagnosis using magnetic resonance (MR) has been focused on the use of structural/anatomical neuroimaging and diffusion tensor imaging (DTI). However, deep brain stimulation, a current strategy for treating PD, is guided by MR imaging (MRI). For clinical prognosis, diagnosis, and follow-up investigations, blood oxygen level-dependent MRI, DTI, spectroscopy, and transcranial magnetic stimulation have been used. These techniques represent the state of the art in the last 5 years. Here, we focus on MR techniques for the diagnosis and treatment of Parkinson's disease.
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Benito de Celis Alonso, Silvia S. Hidalgo-Tobón and Oscar Arias-Carrión have contributed equally to this work.
Reviewed by: Tifei Yuan, Nanjing Normal University, China; Paola Imbriani, University of Rome Tor Vergata, Italy
Specialty section: This article was submitted to Movement Disorders, a section of the journal Frontiers in Neurology
Edited by: Antonio Pisani, University of Rome Tor Vergata, Italy
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2015.00146