Novel Hybrid of Typical Enteropathogenic Escherichia coli and Shiga-Toxin-Producing E. coli (tEPEC/STEC) Emerging From Pet Birds

Exotic psittacine birds have been implicated as reservoir of diarrheagenic ( ), including enteropathogenic (EPEC) and Shiga-toxin producing (STEC). Here, we present a genotypic and phenotypic characterization of typical EPEC/STEC hybrid strains isolated from exotic psittacine birds. The strains were...

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Published inFrontiers in microbiology Vol. 9; p. 2975
Main Authors Gioia-Di Chiacchio, Rosely Martins, Cunha, Marcos Paulo Vieira, de Sá, Lilian Rose Marques, Davies, Yamê Minieiro, Pereira, Camila Bueno Pacheco, Martins, Fernando Henrique, Munhoz, Danielle Dias, Abe, Cecilia Mari, Franzolin, Marcia Regina, Dos Santos, Luis Fernando, Guth, Beatriz Ernestina Cabilio, Elias, Waldir Pereira, Piazza, Roxane Maria Fontes, Knöbl, Terezinha
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 06.12.2018
Subjects
animal diseases
diarrheagenic E. coli
Microbiology
psittacine birds
public health
zoonosis
animal diseases
psittacine birds
zoonosis
diarrheagenic E. coli
public health
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Summary:Exotic psittacine birds have been implicated as reservoir of diarrheagenic ( ), including enteropathogenic (EPEC) and Shiga-toxin producing (STEC). Here, we present a genotypic and phenotypic characterization of typical EPEC/STEC hybrid strains isolated from exotic psittacine birds. The strains were positive for , A, and s 2f genes, belong to serotype O137:H6 and ST2678. Two strains were subject to whole genome sequencing, confirming the presence of the virulence factors of both pathotypes. Phenotypical tests confirmed their ability to adhere to HeLa cells and cause cytotoxicity to Vero cells. The rabbit ileal loop assays showed the attaching and effacing lesion, in addition to inflammatory process and overproduction of intestinal mucus. This is the first report of hybrid typical EPEC/STEC (O137:H6/ST2678) strains isolated from companion psittacine birds and the results suggest zoonotic risks.
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This article was submitted to Infectious Diseases, a section of the journal Frontiers in Microbiology
Reviewed by: Maite Muniesa, University of Barcelona, Spain; Roberto Mauricio Vidal, Universidad de Chile, Chile
Edited by: Jorge Blanco, Universidade de Santiago de Compostela, Spain
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2018.02975