Establishment of an induced pluripotent stem cell line (SDCHi001-A) from a healthy Chinese child donor

We recruited a healthy 6-year-old Chinese Han male, obtained his peripheral blood mononuclear cells (PBMCs) and successfully established induced pluripotent stem cells (iPSC) line using non-integrated reprogramming technology. The iPSC line possessed normal karyotype, expressed pluripotency markers...

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Bibliographic Details
Published inStem cell research Vol. 74; p. 103278
Main Authors Wang, Ling, Zeng, Qian, Wang, Shuyun, Wu, Dan, Wang, Juan, Zhang, Haiyan, Lv, Xin
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 01.02.2024
Elsevier
Subjects
Cell Differentiation
Cell Line
Cellular Reprogramming
Child
China
Humans
Induced Pluripotent Stem Cells - metabolism
Leukocytes, Mononuclear - metabolism
Male
China
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Summary:We recruited a healthy 6-year-old Chinese Han male, obtained his peripheral blood mononuclear cells (PBMCs) and successfully established induced pluripotent stem cells (iPSC) line using non-integrated reprogramming technology. The iPSC line possessed normal karyotype, expressed pluripotency markers and could differentiate into three germ layers in vitro. This cell line will serve as an available control in the research of molecular pathogenesis and a basis for disease modeling.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2023.103278