Cancer Omics in Africa: Present and Prospects

During the last century, cancer biology has been arguably one of the most investigated research fields. To gain deeper insight into cancer mechanisms, scientists have been attempting to integrate multi omics data in cancer research. Cancer genomics, transcriptomics, metabolomics, proteomics, and meta...

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Published inFrontiers in oncology Vol. 10; p. 606428
Main Authors El Jaddaoui, Islam, Allali, Imane, Sehli, Sofia, Ouldim, Karim, Hamdi, Salsabil, Al Idrissi, Najib, Nejjari, Chakib, Amzazi, Saaïd, Bakri, Youssef, Ghazal, Hassan
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 14.12.2020
Subjects
cancer genomics
epigenomics
metabolomics
multi omics
Oncology
proteomics
transcriptomics
multi omics
proteomics
metabolomics
metagenomics
African continent
transcriptomics
cancer genomics
epigenomics
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Summary:During the last century, cancer biology has been arguably one of the most investigated research fields. To gain deeper insight into cancer mechanisms, scientists have been attempting to integrate multi omics data in cancer research. Cancer genomics, transcriptomics, metabolomics, proteomics, and metagenomics are the main multi omics strategies used currently in the diagnosis, prognosis, treatment, and biomarker discovery in cancer. In this review, we describe the use of different multi omics strategies in cancer research in the African continent and discuss the main challenges facing the implementation of these approaches in African countries such as the lack of training programs in bioinformatics in general and omics strategies in particular and suggest paths to address deficiencies. As a way forward, we advocate for the establishment of an "African Cancer Genomics Consortium" to promote intracontinental collaborative projects and enhance engagement in research activities that address indigenous aspects for cancer precision medicine.
Bibliography:Edited by: Dana Kristjansson, Norwegian Institute of Public Health (NIPH), Norway
This article was submitted to Cancer Epidemiology and Prevention, a section of the journal Frontiers in Oncology
Reviewed by: Moray Campbell, Orenburg State University, Russia; Enrique Velazquez-Villarreal, University of Southern California, United States
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2020.606428