Transport calculations for light scattering in blood

In vivo measurement of the oxygen saturation levels in blood may be obtained from relative amounts of backscattered monochromatic light at two different wavelengths, as measured with a fiber-optic catheter oximeter. Because of the short mean free path length of light in blood, the backscattering can...

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Bibliographic Details
Published inBiophysical journal Vol. 16; no. 3; pp. 199 - 207
Main Authors Pedersen, G.D., McCormick, N.J., Reynolds, L.O.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.03.1976
Subjects
Animals
Light
Mathematics
Methods
Oxygen - blood
Scattering, Radiation
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Summary:In vivo measurement of the oxygen saturation levels in blood may be obtained from relative amounts of backscattered monochromatic light at two different wavelengths, as measured with a fiber-optic catheter oximeter. Because of the short mean free path length of light in blood, the backscattering can be well approximated by a previously-derived, one-wavelength transport theory solution for the half-space searchlight problem. This solution, unlike simple diffusion approximations has the advantage that the boundary condition describing illumination of a localized area of blood by a monodirectional light beam can be rigorously satisfied. Sample calculations using the solution are compared with experimental values of the reflectance of blood.
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ISSN:0006-3495
1542-0086
DOI:10.1016/S0006-3495(76)85681-0