Cephalexin Induced Cholestatic Jaundice

Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including el...

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Published inCase reports in gastrointestinal medicine Vol. 2014; no. 2014; pp. 1 - 3
Main Authors Agrawal, Abhinav, Rao, Mana, Jasdanwala, Sarfaraz, Mathur, Ajay, Eng, Margaret
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Puplishing Corporation 01.01.2014
Hindawi Publishing Corporation
Hindawi Limited
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Case Report
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Summary:Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including elevated liver function tests (LFTs) after taking cephalexin and showed improvement on removal of the offending agent. During this time he was symptomatically treated with cholestyramine. Complete resolution of LFTs was seen in four weeks. Cephalexin induced cholestasis is rare and hence requires a high degree of clinical suspicion for prompt diagnosis and treatment.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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Academic Editor: Matteo Neri
ISSN:2090-6528
2090-6536
DOI:10.1155/2014/260743