role of taurine in renal disorders

This article examines the actions of taurine on models of renal dysfunction, the potential mechanisms of taurine action and the possible clinical significance of these findings. Our laboratory has written previously on the role of taurine in renal function and we have focused upon the normal physiol...

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Bibliographic Details
Published inAmino acids Vol. 43; no. 6; pp. 2249 - 2263
Main Authors Han, Xiaobin, Chesney, Russell W
Format Journal Article
LanguageEnglish
Published Vienna Springer-Verlag 01.12.2012
Springer Vienna
Springer Nature B.V
Subjects
Amino acids
Analytical Chemistry
Animals
Biochemical Engineering
Biochemistry
Biomedical and Life Sciences
Chronic infection
Control
Diabetes mellitus
diabetic nephropathy
Disorders
Humans
Hypertension
Invited Review
Kidney diseases
Kidney Diseases - drug therapy
Kidney Diseases - metabolism
Kidney Diseases - physiopathology
Kidney Function Tests
kidney transplant
Kidney transplantation
Kidneys
Life Sciences
Nephrolithiasis
Nephropathy
Neurobiology
Proteinuria
Proteomics
Recognition
renal calculi
Renal function
Taurine
Taurine - metabolism
Taurine - therapeutic use
Urinary tract
Taurine
Diabetic nephropathy
Chronic kidney disease
Renal function
Glomerular nephritis
Acute kidney injury
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Summary:This article examines the actions of taurine on models of renal dysfunction, the potential mechanisms of taurine action and the possible clinical significance of these findings. Our laboratory has written previously on the role of taurine in renal function and we have focused upon the normal physiology of the kidney and on the mechanisms and regulation of the renal transport of taurine. This review is a distinct change of emphasis in that we describe a number of studies which have evaluated various aspects of renal dysfunction, including hypertension and proteinuria, specific glomerular and tubular disorders, acute and chronic renal conditions, urinary tract conditions including infection and nephrolithiasis, and diabetic nephropathy. The subject of chronic kidney disease and renal transplantation will also be examined relative to β amino acid. The studies evaluated will be mainly recent ones, recognizing that older reviews of the role of this taurine in the kidney are available.
Bibliography:http://dx.doi.org/10.1007/s00726-012-1314-y
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ISSN:0939-4451
1438-2199
1438-2199
DOI:10.1007/s00726-012-1314-y