Synthesis of some novel 11b-substituted pyrimido[6,1-a]-isoquinoline derivatives

A series of novel 11b-substituted 1,6,7,11b-tetrahydropyrimido[6,1-a]- isoquinoline-2,4-diones and 4-thioxo-1,3,4,6,7,11b-hexahydropyrimido[6,1-a]isoquinolin-2- ones were synthesized, utilizing two alternative strategies for ring closure of tetrahydroisoquinoline intermediates obtained from N-phenet...

Full description

Saved in:
Bibliographic Details
Published inMolecules (Basel, Switzerland) Vol. 9; no. 8; pp. 694 - 704
Main Authors Angelov, Plamen A, Ivanov, Iliyan I, Venkov, Atanas P
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 31.07.2004
MDPI
Subjects
1-a]isoquinolines
Algorithms
Antihypertensives
enaminones
Magnetic Resonance Spectroscopy
Models, Chemical
Protons
Pyrimidines - chemical synthesis
Pyrimidines - chemistry
pyrimido
Tetrahydroisoquinolines
Tetrahydroisoquinolines - chemical synthesis
Tetrahydroisoquinolines - chemistry
Online AccessGet full text

Cover

More Information
Summary:A series of novel 11b-substituted 1,6,7,11b-tetrahydropyrimido[6,1-a]- isoquinoline-2,4-diones and 4-thioxo-1,3,4,6,7,11b-hexahydropyrimido[6,1-a]isoquinolin-2- ones were synthesized, utilizing two alternative strategies for ring closure of tetrahydroisoquinoline intermediates obtained from N-phenethyl enaminones.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Dr. Venkov passed away on 21.07.2003, while this project was already in progress. We would like to dedicate this paper to his memory.
ISSN:1420-3049
1420-3049
DOI:10.3390/90800694