Metalloporphyrins – An Update

• Published in: Frontiers in pharmacology Vol. 3; p. 68
• Main Authors: Schulz, Stephanie, Wong, Ronald J., Vreman, Hendrik J., Stevenson, David K.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 01.01.2012; Frontiers Media S.A
• Subjects: Bilirubin; heme oxygenase; Hemolysis; Jaundice; Neonatal Hyperbilirubinemia; Pharmacology; heme oxygenase; bilirubin; hemolysis; neonatal hyperbilirubinemia

Metalloporphyrins are structural analogs of heme and their potential use in the management of neonatal hyperbilirubinemia has been the subject of considerable research for more than three decades. The pharmacological basis for using this class of compounds to control bilirubin levels is the targeted...