Radioguided occult lesion localization (ROLL) for non-palpable breast cancer: A comparison between day-before and same-day protocols

• Published in: Breast (Edinburgh) Vol. 19; no. 3; pp. 226 - 230
• Main Authors: Aydogan, Fatih, Ozben, Volkan, Celik, Varol, Uras, Cihan, Tahan, Gülgün, Gazioglu, Ertugrul, Cengiz, Ali, Ferahman, Mehmet, Cercel, Ali, Yilmaz, Mehmet Halit, Halac, Metin, Unal, Hilal
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.06.2010
• Subjects: Adult; Aged; Breast Neoplasms - diagnosis; Breast Neoplasms - surgery; Cohort Studies; Day-before injection; Drug Administration Schedule; Female; Hematology, Oncology and Palliative Medicine; Humans; Mastectomy; Middle Aged; Non-palpable breast cancer; Predictive Value of Tests; Radiopharmaceuticals - administration & dosage; Retrospective Studies; ROLL; Same-day injection; Surgery, Computer-Assisted; Technetium Tc 99m Aggregated Albumin - administration & dosage; ROLL; Non-palpable breast cancer; Same-day injection; Day-before injection
• ISSN: 0960-9776; 1532-3080
• DOI: 10.1016/j.breast.2010.01.017

Abstract Background Although radioguided occult lesion localization (ROLL) has become a widely accepted technique, the optimal time interval between the radioisotope injection and surgery has not yet been determined. Aim To delineate the effects of time from the injection of the radionuclide until surgery on the ROLL success rate in a patient population diagnosed as having non-palpable breast cancer. Methods Between December 2004 and May 2009, 75 patients underwent ROLL procedure. The day-before protocol and same-day protocols included 50 and 25 breast cancer patients respectively. Results The two study groups were comparable in terms of age, localization technique, radiological findings and the type of surgical procedures ( P  >  0.05 ). No statistically significant difference was noticed in the pathological diagnosis, cancer size and the surgical margin clearance between the two groups ( P  >  0.05 ). Conclusions Same-day injection of the radiotracer was not superior to the day-before injection in ROLL. The day-before protocol can be scheduled for the convenience of both patients and hospital staff.