BUMPY STEM Is an Arabidopsis Choline/Ethanolamine Kinase Required for Normal Development and Chilling Responses
Phospholipid biosynthesis is a core metabolic pathway that affects all aspects of plant growth and development. One of the earliest step in this pathway is mediated by choline/ethanolamine kinases (CEKs), enzymes in the Kennedy pathway that catalyze the synthesis of the polar head groups found on th...
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Published in | Frontiers in plant science Vol. 13; p. 851960 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
Frontiers Media S.A
29.04.2022
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Subjects | |
Online Access | Get full text |
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Summary: | Phospholipid biosynthesis is a core metabolic pathway that affects all aspects of plant growth and development. One of the earliest step in this pathway is mediated by choline/ethanolamine kinases (CEKs), enzymes in the Kennedy pathway that catalyze the synthesis of the polar head groups found on the most abundant plant phospholipids. The Arabidopsis genome encodes four
s.
have been well characterized using viable mutants while
encodes an essential gene, making it difficult to characterize its effects on plant development and responses to the environment. We have isolated an EMS-induced allele of
called
(
).
plants are viable, allowing the effects of decreased
function to be characterized throughout the Arabidopsis life cycle.
mutants have a range of developmental defects including ectopic stem growths at the base of their flowers, reduced fertility, and short roots and stems. They are also sensitive to cold temperatures. Supplementation with choline, phosphocholine, ethanolamine, and phosphoethanolamine rescues
root phenotypes, highlighting the flow of metabolites between the choline and ethanolamine branches of the Kennedy pathway. The identification of
and characterization of its phenotypes defines new roles for
that go beyond its established biochemical function as an ethanolamine kinase. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Edited by: Patricia Springer, University of California, Riverside, United States Reviewed by: Ying-Chen Lin, University of Oxford, United Kingdom; Hai Anh Ngo, Institute of Plant and Microbial Biology, Academia Sinica, Taiwan This article was submitted to Plant Development and EvoDevo, a section of the journal Frontiers in Plant Science |
ISSN: | 1664-462X 1664-462X |
DOI: | 10.3389/fpls.2022.851960 |