Mesenchymal cell differentiation during lymph node organogenesis

• Published in: Frontiers in immunology Vol. 3; p. 381
• Main Authors: Brendolan, Andrea, Caamaño, Jorge H
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 01.01.2012
• Subjects: cell-cell interaction; Immunology; Lymphoid Tissue; Lymphotoxin beta Receptor; NF-kappa B; Stromal Cells; lymphotoxin beta receptor; NF-κB; stromal cells; lympho-mesenchymal interactions; lymphoid tissues

Secondary lymphoid tissues such as lymph nodes are essential for the interactions between antigen presenting cells and lymphocytes that result in adaptive immune responses that protect the host against invading pathogens. The specialized architecture of these organs facilitates the cognate interacti...