Bottlenecks to clinical translation of direct brain-computer interfaces

Despite several decades of research into novel brain-implantable devices to treat a range of diseases, only two-cochlear implants for sensorineural hearing loss and deep brain stimulation for movement disorders-have yielded any appreciable clinical benefit. Obstacles to translation include technical...

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Bibliographic Details
Published inFrontiers in systems neuroscience Vol. 8; p. 226
Main Author Serruya, Mijail D
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 02.12.2014
Subjects
Brain Computer Interface
brain machine interface
Commercialization
Device Approval
neuroprosthetics
Neuroscience
device approval
neurotechnology
commercialization
neuroprosthetic
brain-computer interface
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Summary:Despite several decades of research into novel brain-implantable devices to treat a range of diseases, only two-cochlear implants for sensorineural hearing loss and deep brain stimulation for movement disorders-have yielded any appreciable clinical benefit. Obstacles to translation include technical factors (e.g., signal loss due to gliosis or micromotion), lack of awareness of current clinical options for patients that the new therapy must outperform, traversing between federal and corporate funding needed to support clinical trials, and insufficient management expertise. This commentary reviews these obstacles preventing the translation of promising new neurotechnologies into clinical application and suggests some principles that interdisciplinary teams in academia and industry could adopt to enhance their chances of success.
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Reviewed by: Mikhail Lebedev, Duke University, USA; Dong Song, University of Southern California, USA
This article was submitted to the journal Frontiers in Systems Neuroscience.
Edited by: Ioan Opris, Wake Forest University, USA
ISSN:1662-5137
1662-5137
DOI:10.3389/fnsys.2014.00226