Pulse width modulation-based TMS: Primary motor cortex responses compared to conventional monophasic stimuli

•The PWM method enables the digital synthesis of TMS patterns and shapes.•Suprathreshold PWM magnetic pulses were well tolerated by the participants without adverse events.•RMTs and MEPs were compared for PWM and conventional stimuli.•Thresholds were 3% lower with PWM pulses than with conventional p...

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Bibliographic Details
Published inBrain stimulation Vol. 15; no. 4; pp. 980 - 983
Main Authors Memarian Sorkhabi, Majid, Wendt, Karen, O'Shea, Jacinta, Denison, Timothy
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.07.2022
Elsevier
Subjects
Evoked Potentials, Motor - physiology
Heart Rate
Motor Cortex - physiology
Transcranial Magnetic Stimulation
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Summary:•The PWM method enables the digital synthesis of TMS patterns and shapes.•Suprathreshold PWM magnetic pulses were well tolerated by the participants without adverse events.•RMTs and MEPs were compared for PWM and conventional stimuli.•Thresholds were 3% lower with PWM pulses than with conventional pulses.
Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:1935-861X
1876-4754
DOI:10.1016/j.brs.2022.06.013